Our lab exploits whole genome approaches to tackle problems in yeast molecular biology and human infectious disease. These projects can be classified into three separate areas:
Dr. Sandy Feng is a transplant surgeon who performs liver, kidney and pancreas transplants.
In her research, Feng studies transplantation tolerance, a transplant recipient's ability to maintain normal organ function with minimal or no use of immunosuppressive drugs. With funding from the National Institutes of Health, she has led several multicenter clinical trials to study tolerance in both adult and pediatric liver transplant recipients.
Dr. Emily R. Perito is an professor at UCSF who specializes in pediatric liver and pancreatic disease, pediatric liver transplant, and pediatric gastroenterology. She is jointly appointed in the Departments of Pediatrics and of Epidemiology and Biostatistics and affiliated faculty with the Institute for Health Policy Studies. She is board-certified in pediatrics, pediatric gastroenterology, and pediatric transplant hepatology.
Michele Tana grew up in Northern Virginia, studied the Classics at Harvard College, and attended Harvard Medical School. She trained in Internal Medicine at Stanford University Hospital and Clinics and Gastroenterology at California Pacific Medical Center. She was a Hepatology Fellow at the National Institutes of Health in the National Institute of Diabetes and Digestive and Kidney Diseases and earned a Masters Degree in Clinical Research from Duke University.
My lab studies how the different cell types in the liver, in particular the hepatocyte, are generated during development, patterned and maintained during adulthood, and regenerate after injury. Our long-term goals are to improve the understanding of liver disease pathophysiology and develop novel methods of treatment for liver diseases, including cell replacement therapy. Currently, we have two major research focuses: 1) understanding the biology of adult hepatocyte stem cells and 2) developing a liver cell atlas.
